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石棉暴露与相关肿瘤形成。一家大型城市医院的28年经验。

Asbestos exposure and related neoplasia. The 28 year experience of a major urban hospital.

作者信息

Hasan F M, Nash G, Kazemi H

出版信息

Am J Med. 1978 Oct;65(4):649-54. doi: 10.1016/0002-9343(78)90853-7.

DOI:10.1016/0002-9343(78)90853-7
PMID:707524
Abstract

In a retrospective study of 49 cases of asbestosis, a steady increase in the frequency of diagnosis of asbestosis and asbestos-related neoplasia is documented from a major urban hospital since 1960. Although in the majority of cases the subjects were exposed to asbestos in a neighboring shipyard, in 20 per cent of the cases, asbestos exposure was in industries not related to shipbuilding, reflecting its widespread use. This selective population of patients with asbestosis more often than not had an associated neoplasm. The most likely accompanying tumor was pleural mesothelioma, and among cell types of lung cancer, adenocarcinoma was notably frequent.

摘要

在一项对49例石棉沉着病患者的回顾性研究中,自1960年以来,一家大型城市医院记录到石棉沉着病及石棉相关肿瘤的诊断频率稳步上升。尽管大多数病例中的患者是在附近造船厂接触石棉的,但在20%的病例中,石棉暴露发生在与造船无关的行业,这反映了石棉的广泛使用。这群患石棉沉着病的患者往往伴有肿瘤。最可能伴随的肿瘤是胸膜间皮瘤,在肺癌的细胞类型中,腺癌尤为常见。

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Asbestos exposure and related neoplasia. The 28 year experience of a major urban hospital.石棉暴露与相关肿瘤形成。一家大型城市医院的28年经验。
Am J Med. 1978 Oct;65(4):649-54. doi: 10.1016/0002-9343(78)90853-7.
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[Not Available].[无可用内容]。
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Asbestos-related diseases of lung and pleura: clinical picture and illustrative cases.石棉相关的肺和胸膜疾病:临床表现及病例展示
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Lung asbestos burden in shipyard and construction workers with mesothelioma: comparison with burdens in subjects with asbestosis or lung cancer.患有间皮瘤的造船厂和建筑工人的肺部石棉负荷:与石棉肺或肺癌患者的负荷比较。
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[Respiratory malignancies induced by asbestos exposure and evaluation of cases with typical pleural malignant mesothelioma and lung cancer with asbestosis].[石棉暴露所致呼吸道恶性肿瘤及典型胸膜恶性间皮瘤与石棉沉着病合并肺癌病例的评估]
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引用本文的文献

1
Asbestos bodies in the lung: Southampton (UK) and Wellington (New Zealand).肺部的石棉小体:英国南安普顿和新西兰惠灵顿
Br J Ind Med. 1982 Nov;39(4):349-54. doi: 10.1136/oem.39.4.349.
2
Is asbestos or asbestosis the cause of the increased risk of lung cancer in asbestos workers?石棉或石棉沉着病是导致石棉工人肺癌风险增加的原因吗?
Br J Ind Med. 1986 Mar;43(3):145-9. doi: 10.1136/oem.43.3.145.
3
Correlation of in vitro genotoxicity and oncogenicity induced by radiation and asbestos fibres.辐射与石棉纤维诱导的体外遗传毒性和致癌性的相关性。
Br J Cancer. 1985 Oct;52(4):591-7. doi: 10.1038/bjc.1985.231.