Müller-Esch G, Brunk E, Djonlagic H, Hoffmann J, Wiessmann K J
Dtsch Med Wochenschr. 1982 May 7;107(18):692-5. doi: 10.1055/s-2008-1070004.
After inhaling a leather-impregnation spray in a confined space, coughing fits and dyspnoea occurred in a 40-year-old man and an 20-year-old woman, previously in good health. The cardinal symptoms on admission to an emergency ward were of interstitial pulmonary oedema in the X-ray but without increased pulmonary arterial pressure. Administration of corticosteroids both by aerosol and intravenously improved the acute symptoms within a few hours. Two subsequent chest X-rays demonstrated complete healing. The acute symptoms were caused by the impregnation spray producing an alveolitis or toxic lung oedema in both cases. The early topical administration of corticosteroids would appear to be the most important preventive and protective measure.
在一个密闭空间吸入皮革浸渍喷雾剂后，一名40岁健康男性和一名20岁健康女性出现了阵阵咳嗽和呼吸困难。急诊病房收治时的主要症状在X射线下显示为间质性肺水肿，但肺动脉压未升高。通过气雾剂和静脉注射给予皮质类固醇在数小时内改善了急性症状。随后的两次胸部X线检查显示完全康复。急性症状是由浸渍喷雾剂在两例中导致肺泡炎或中毒性肺水肿引起的。早期局部应用皮质类固醇似乎是最重要的预防和保护措施。
