Kassil' V G, Butkevich I P
Fiziol Zh SSSR Im I M Sechenova. 1982 Feb;68(2):187-91.
Bilateral supradiaphragmal section of the vagus nerves in 21 puppies and 12 adult dogs abolished adverse responses to selfstimulation of the lateral hypothalamus. The vagotomy led to facilitation (lowering of threshold, increase in the rate of leverpressing) of the self-stimulation of the posterior-lateral hypothalamic area which was most obvious and stable in the 8-12 week old puppies and adult dogs. When placing the electrodes in the anterior hypothalamic areas and related emotiogenic cerebral structures, the self-stimulation threshold increased. Therefore, the afferent effects on the vagus nerves can both inhibit and facilitate activity of the cerebral areas related to positive reinforcement and connected mainly with the posterior of anterior hypothalamic areas.
对21只幼犬和12只成年犬进行双侧膈上迷走神经切断术，消除了对下丘脑外侧自我刺激的不良反应。迷走神经切断术导致下丘脑后外侧区域自我刺激的易化（阈值降低、按压杠杆速率增加），这在8 - 12周龄的幼犬和成年犬中最为明显和稳定。当将电极置于下丘脑前部区域及相关的情绪发生性脑结构时，自我刺激阈值升高。因此，迷走神经的传入效应既能抑制也能易化与正性强化相关且主要与下丘脑前部后部相连的脑区的活动。
