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一氧化碳的死后形成

Postmortem formation of carbon monoxide.

作者信息

Kojima T, Nishiyama Y, Yashiki M, Une I

出版信息

Forensic Sci Int. 1982 May-Jun;19(3):243-8. doi: 10.1016/0379-0738(82)90085-8.

DOI:10.1016/0379-0738(82)90085-8
PMID:7076067
Abstract

Since carbon monoxide (CO) production after death was suggested in a drowned body, CO and carboxyhemoglobin (HbCO) levels in blood and body cavity fluids of cadavers which were not exposed to fire and CO hve been analyzed. CO released from the tissues was determined by gas chromatography and gas chromatography-mass spectrometry, and the total concentration of hemoglobin (Hb) was measured as cyanmethemoglobin (CNmHb). The HbCO level was calculated by the ratio of CO content and CO-binding capacity. CO levels (ml/100 g at STP) of the seven cases in which blood and body cavity fluids could be collected ranged from 0.13 to 0.87 in blood and 0.02 to 0.80 in body cavity fluids. HbCO levels in blood and body cavity fluids were from 0.3 to 6.0% and from 2.3 to 44.1%, respectively. In a typical case showing postmortem formation of CO, the CO levels in body cavity fluids were higher than that in blood. It is suggested that CO in a putrefied body is due to CO in blood prior to death and the CO formed by the decomposition of Hb, myoglobin and other substances during putrefaction. The significance of HbCO levels in body cavity fluids of cases with marked postmortem decomposition seems difficult to interpret without the value of HbCO in blood.

摘要

由于有研究表明溺亡尸体在死后会产生一氧化碳(CO),因此对未接触过火灾和一氧化碳的尸体血液及体腔液中的CO和碳氧血红蛋白(HbCO)水平进行了分析。通过气相色谱法和气相色谱-质谱法测定组织释放的CO,并将血红蛋白(Hb)的总浓度测定为氰化高铁血红蛋白(CNmHb)。HbCO水平通过CO含量与CO结合能力的比值计算得出。在可采集血液和体腔液的7例病例中,血液中的CO水平(标准温度和压力下每100克毫升数)为0.13至0.87,体腔液中的CO水平为0.02至0.80。血液和体腔液中的HbCO水平分别为0.3%至6.0%和2.3%至44.1%。在一个显示死后形成CO的典型病例中,体腔液中的CO水平高于血液中的CO水平。提示腐败尸体中的CO源于死亡前血液中的CO以及腐败过程中Hb、肌红蛋白和其他物质分解产生的CO。对于死后显著腐败的病例,若无血液中HbCO的值,似乎难以解释体腔液中HbCO水平的意义。

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Postmortem formation of carbon monoxide.一氧化碳的死后形成
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Production of carbon monoxide in cadavers.尸体中一氧化碳的产生。
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Experimental study on postmortem formation of carbon monoxide.一氧化碳死后形成的实验研究
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Postmortem formation of carbon monoxide in blood and body cavity fluids of rats drowned and kept immersed in fresh water.溺水并浸泡于淡水中的大鼠血液及体腔液中一氧化碳的死后生成情况
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Sample pre-treatment for CO-oximetric determination of carboxyhaemoglobin in putrefied blood and cavity fluid.用于一氧化碳血氧定量法测定腐败血液和体腔液中碳氧血红蛋白的样本预处理。
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Postmortem concentrations for total blood carbon monoxide (TBCO) as a novel biomarker for carbon monoxide (CO) poisonings.死后全血一氧化碳(TBCO)浓度作为一氧化碳(CO)中毒的新型生物标志物。
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