Vassall-Adams P R
J Anat. 1982 Jan;134(Pt 1):169-83.
A light microscopic study of serial sections of the hearts of 64 avian embryos (chicken, turkey, duck and goose) was undertaken in order to elucidate the development of the atrioventricular bundle and its branches. The developing atrioventricular bundle and its branches were shown to appear simultaneously (at about a third of the way through incubation) as relatively large, discrete fasciculi, which were dark-staining when compared with developing cardiac muscle. Prior to the appearance of the bundle and branches, the developing conducting tissue was found to be present as a widespread precursor tissue, which was distributed as a complete, dark-staining subendocardial sleeve, lining the whole of the ventricular canal, ventriculobulbar loop, and extending into the common atrial cavity. From these observations, it is concluded that, with septation and chamber formation, the tissue of the sleeve is partly incorporated within the chamber walls to give origin to diffuse Purkinje tissue, and is partly retained as the bundle and branches. The manner of derivation of the bundle and branches is discussed, and it is stressed that the definitive positions of the bundle and branches denote the junctional zones of the components of septation.
为阐明房室束及其分支的发育情况，对64个禽类胚胎（鸡、火鸡、鸭和鹅）心脏的连续切片进行了光学显微镜研究。发育中的房室束及其分支显示为同时出现（约在孵化过程的三分之一阶段），呈相对较大的离散束状，与发育中的心肌相比，染色较深。在束和分支出现之前，发现发育中的传导组织以广泛的前体组织形式存在，它作为完整的、染色较深的内膜下套分布，衬于整个心室管、心室球袢，并延伸至共同心房腔。从这些观察结果得出结论，随着分隔和腔室形成，套组织部分并入腔室壁以产生弥漫性浦肯野组织，部分保留为束和分支。文中讨论了束和分支的衍生方式，并强调束和分支的最终位置表示分隔成分的交界区。
