Nistal M, Abaurrea M A, Paniagua R
J Anat. 1982 Mar;134(Pt 2):351-63.
In order to evaluate the changes in the number and form of the Sertoli cell from birth to the onset of puberty, a histometric and ultrastructural study was carried out in normal children. Ultrastructural findings revealed that immature Sertoli cells, present from birth to puberty, show round to elliptical nuclei, with regular outlines and small nucleoli. The cytoplasm exhibits well developed rough endoplasmic reticulum, prominent supranuclear Golgi complexes and vesicles at the luminal face; smooth endoplasmic reticulum was scarce. Histometric study revealed a progressive decrease in the Sertoli cell number per transverse tubular section as well as per unit area of testicular parenchyma, mainly from 3 years onwards. However, this decrease seemed to be the result of the progressive increase in the testicular volume as well as in the length and width of the seminiferous tubules, without change in the total Sertoli cell number per testis. This number may be considered constant, not only for adult testes but also for postnatal developing testes.
为了评估从出生到青春期开始时支持细胞数量和形态的变化，对正常儿童进行了组织形态计量学和超微结构研究。超微结构研究结果显示，从出生到青春期存在的未成熟支持细胞，其细胞核呈圆形至椭圆形，轮廓规则，核仁较小。细胞质中粗面内质网发达，核上高尔基体复合体突出，管腔面有小泡；滑面内质网稀少。组织形态计量学研究显示，主要从3岁起，每横断小管切片以及每单位睾丸实质面积中的支持细胞数量逐渐减少。然而，这种减少似乎是睾丸体积以及生精小管长度和宽度逐渐增加的结果，而每个睾丸中支持细胞的总数没有变化。这个数量不仅对于成年睾丸，而且对于出生后发育中的睾丸都可认为是恒定的。
