Mårtensson J
Metabolism. 1982 May;31(5):487-92. doi: 10.1016/0026-0495(82)90239-6.
The urinary excretion of sulfur-containing compounds was studied before, on the third, and on the seventh day of fasting in 10 healthy subjects. The excretion of total sulfur, inorganic sulfate, ester sulfate, "non-sulfate sulfur", methionine, cystathionine, cysteine, N-acetylcysteine, taurine, thiosulfate and thiocyanate was decreased during fasting, whereas the excretion of mercaptoacetate was unaltered and that of mercaptolactate increased. The excretion of inorganic sulfate, taurine and thiocyanate was also decreased when calculated relative to that of total sulfur, suggesting that these compounds are derived mainly from dietary sulfur amino acids. The output of ester sulfate, methionine, cystathionine, cysteine and thiosulfate was unaltered in relation to that of total sulfur, indicating that these compounds are derived from both dietary and endogenous sulfur amino acids, liberated during protein catabolism. By contrast, the excretion of mercaptolactate and mercaptoacetate was increased relative to that of total sulfur, suggesting that these compounds are derived mainly from endogenous sulfur amino acids formed by the enhanced protein catabolism seen during fasting.
对10名健康受试者在禁食前、禁食第三天和第七天的含硫化合物尿排泄情况进行了研究。禁食期间，总硫、无机硫酸盐、硫酸酯、“非硫酸盐硫”、蛋氨酸、胱硫醚、半胱氨酸、N - 乙酰半胱氨酸、牛磺酸、硫代硫酸盐和硫氰酸盐的排泄量减少，而巯基乙酸的排泄量未改变，巯基乳酸的排泄量增加。当相对于总硫的排泄量计算时，无机硫酸盐、牛磺酸和硫氰酸盐的排泄量也减少，这表明这些化合物主要来源于膳食中的含硫氨基酸。硫酸酯、蛋氨酸、胱硫醚、半胱氨酸和硫代硫酸盐的排泄量相对于总硫的排泄量未改变，这表明这些化合物来源于膳食和内源性含硫氨基酸，在蛋白质分解代谢过程中释放出来。相比之下，巯基乳酸和巯基乙酸相对于总硫的排泄量增加，这表明这些化合物主要来源于禁食期间蛋白质分解代谢增强所形成的内源性含硫氨基酸。
