Andersen D W, Filer L J, Wu-Rideout Y C, White L B, Stegink L D
Pediatr Res. 1982 Apr;16(4 Pt 1):304-9. doi: 10.1203/00006450-198204000-00013.
The ability of intravenously administered glucose or glucose oligosaccharides to supply 12% of the energy requirement of the growing miniature pig was determined. All pigs were fed a stock diet from days 5-28 of life, and a central venous catheter was inserted at 29 days. For the next 30 days, all pigs were fed both enterally and parenterally. Positive control pigs were fed the stock diet with infusions of an isotonic balanced electrolyte solution. Negative control and test animals were fed a diet containing cellulose to replace 12% of energy. Negative control animals received the balanced electrolyte solution intravenously, while test animals received either intravenous glucose of glucose oligosaccharides at levels providing 12% of energy. Carbohydrate utilization was measured by urinary loss of carbohydrate, as well as by growth and body composition. Chemical analyses of the urine indicated utilization of both glucose and glucose oligosaccharides. Glucose oligosaccharides were utilized less well (85%) than glucose (greater than or equal to 99%). No statistically significant differences in weight gain were noted between groups, although weight gain in negative control animals and those animals infused with glucose oligosaccharide solutions were lower than those in the other groups. Body fat analyses also indicated that glucose oligosaccharide solutions were less effective than glucose as an energy source.
测定了静脉注射葡萄糖或低聚葡萄糖为生长中的小型猪提供12%能量需求的能力。所有仔猪在出生后第5至28天饲喂基础日粮，并在第29天插入中心静脉导管。在接下来的30天里，所有仔猪同时进行肠内和肠外营养。阳性对照仔猪饲喂基础日粮并输注等渗平衡电解质溶液。阴性对照和试验动物饲喂含有纤维素的日粮以替代12%的能量。阴性对照动物静脉注射平衡电解质溶液，而试验动物静脉注射葡萄糖或低聚葡萄糖，剂量为提供12%的能量。通过碳水化合物的尿排泄量以及生长和身体组成来测定碳水化合物的利用率。尿液的化学分析表明葡萄糖和低聚葡萄糖均被利用。低聚葡萄糖的利用率（85%）低于葡萄糖（大于或等于99%）。尽管阴性对照动物和输注低聚葡萄糖溶液的动物体重增加低于其他组，但各组之间体重增加无统计学显著差异。体脂分析还表明，低聚葡萄糖溶液作为能量来源不如葡萄糖有效。
