Andersen D W, Filer L J, Stegink L D
J Nutr. 1983 Feb;113(2):430-5. doi: 10.1093/jn/113.2.430.
The ability of fed or fasted 30-day-old pigs to utilize intravenously administered glucose-oligosaccharides (supplied at 20 g/day) was compared in a randomized crossover design. Six pigs were fed a stock diet from days 10 to 30 of life. A central venous catheter was placed on day 30. From days 30 to 39 of life, either a balanced electrolyte solution or a glucose-oligosaccharide solution was infused through the intravenous (i.v.) catheter. On the first i.v. feeding day, all animals were infused with an isotonic, balanced electrolyte solution and were allowed food and water ad libitum per os. On days 2 through 5 of the i.v. period, 3 animals received glucose-oligosaccharides intravenously (20 g/day), with all other needed nutrients, including energy, supplied enterally. On days 6-9 of the i.v. infusion period these animals continued to receive oligosaccharides intravenously, but were denied food. The other three animals were infused with oligosaccharides in the fed or fasting state in the reverse order. Based on urinary carbohydrate excretion, mean (+/- SD) glucose-oligosaccharide utilization was 92% whether the animals were fed or fasted. These results differ from those observed in fasted human subjects.
采用随机交叉设计比较了30日龄仔猪在喂食或禁食状态下利用静脉注射葡萄糖低聚糖（每天供应20克）的能力。6头仔猪在出生后第10天至第30天喂食基础日粮。在第30天放置中心静脉导管。从出生后第30天至第39天，通过静脉导管输注平衡电解质溶液或葡萄糖低聚糖溶液。在首次静脉喂食日，所有动物均输注等渗平衡电解质溶液，并允许经口自由采食食物和饮水。在静脉输注期的第2天至第5天，3头动物静脉注射葡萄糖低聚糖（每天20克），所有其他必需营养素（包括能量）经肠道供应。在静脉输注期的第6 - 9天，这些动物继续静脉接受低聚糖，但禁食。另外3头动物以相反顺序在喂食或禁食状态下输注低聚糖。根据尿中碳水化合物排泄量，无论动物处于喂食还是禁食状态，平均（±标准差）葡萄糖低聚糖利用率均为92%。这些结果与在禁食人类受试者中观察到的结果不同。
