DeCesare J A, Babchyck B M, Colten H R, Treves S
Phys Ther. 1982 Jun;62(6):820-7. doi: 10.1093/ptj/62.6.820.
This study assesses the use of krypton 81m scintigraphy as a measurement tool in evaluating the effectiveness of bronchial drainage with percussion and vibration on peripheral ventilation in patients with cystic fibrosis. Ten patients with cystic fibrosis participated. Each patient underwent a krypton 81m ventilation study and traditional pulmonary function tests. Forty-five minutes later, these studies were repeated before and after a chest physical therapy treatment. Each patient acted as his own control. All krypton 81m scintiscans were recorded and analyzed visually and numerically using a digital computer to assess distribution of ventilation. Visual analysis of the scintiscans indicated individual variation in treatment response: in some patients ventilation improved with therapy; in others, no change was noted; still others had changes independent of treatment. Numerical data derived from the scintiscans and pulmonary function tests showed no important differences among the three studies of each patient. Airway abnormalities characteristic of cystic fibrosis, progression of the disease, sputum production, or a combination of these factors may account for the individual variation in response to treatment. Krypton 81m scintigraphy is a reliable measure of regional ventilation and should be useful for assessing the efficacy of chest physical therapy because of the consistent, high quality visual data retrieved.
本研究评估了氪81m闪烁扫描作为一种测量工具，用于评估囊性纤维化患者通过叩击和振动进行支气管引流对周围通气的有效性。十名囊性纤维化患者参与了研究。每位患者都接受了氪81m通气研究和传统肺功能测试。45分钟后，在胸部物理治疗前后再次进行这些研究。每位患者都作为自己的对照。所有氪81m闪烁扫描图像均被记录下来，并使用数字计算机进行视觉和数值分析，以评估通气分布情况。闪烁扫描图像的视觉分析表明，治疗反应存在个体差异：在一些患者中，通气功能通过治疗得到改善；在另一些患者中，未观察到变化；还有一些患者的变化与治疗无关。从闪烁扫描图像和肺功能测试得出的数值数据显示，每位患者的三项研究之间没有显著差异。囊性纤维化特有的气道异常、疾病病情进展，疾病进展、痰液产生或这些因素的综合作用可能是导致治疗反应个体差异的原因。氪81m闪烁扫描是区域通气的可靠测量方法，由于可获取一致、高质量的视觉数据，因此应有助于评估胸部物理治疗的疗效。
