Ehrlein H J, Hiesinger E
Q J Exp Physiol. 1982 Jan;67(1):17-29. doi: 10.1113/expphysiol.1982.sp002611.
In four conscious dogs mechanical activity of the gastroduodenal junction was recorded with chronically implanted strain gauge transducers and induction coils. The data were evaluated by a computer. Analog circuits were used in order to reduce the data which were transferred to the computer. In the digestive state the contractions of the pyloric sphincter and duodenal bulb were correlated in such a way that the contractions of the duodenal bulb were inhibited when the gastric waves travelled across the antrum and that the bulb contracted once or twice when the peristaltic waves arrived at the gastroduodenal junction. However, the timing between pyloric and duodenal contractions was imperfect. Contraction maxima of the duodenal bulb often occurred before the pylorus was closed. This was due to the different inherent frequencies of the pyloric and duodenal contractions. In the interdigestive state the timing between the pyloric and duodenal contractions was as imperfect as during the digestive state. In phase III of the interdigestive activity, however, the strong antral contractions were regularly associated with inhibition of the duodenal bulb. This phenomenon can be interpreted as co-ordination between gastric and duodenal activity.
在四只清醒的犬中，用长期植入的应变片式传感器和感应线圈记录胃十二指肠连接处的机械活动。数据由计算机进行评估。使用模拟电路以减少传输到计算机的数据。在消化状态下，幽门括约肌和十二指肠球部的收缩存在相关性，即当胃波穿过胃窦时十二指肠球部的收缩受到抑制，而当蠕动波到达胃十二指肠连接处时球部会收缩一到两次。然而，幽门和十二指肠收缩之间的时间间隔并不完美。十二指肠球部的收缩最大值常常在幽门关闭之前出现。这是由于幽门和十二指肠收缩的固有频率不同。在消化间期状态下，幽门和十二指肠收缩之间的时间间隔与消化状态下一样不完美。然而，在消化间期活动的第三阶段，强烈的胃窦收缩与十二指肠球部的抑制有规律地相关联。这种现象可解释为胃和十二指肠活动之间的协调。
