[Acid phosphatase isoenzyme composition of the lysosomes of normal and tumor cells].

Heterogeneity of acid phosphatase in lysosomes of the rat's liver and the Zhaidel hepatoma was studied by the DEAE-cellulose chromatography. It is found that different substrates are hydrolyzed by different molecular forms of the enzyme. It is suggested that variability in the increase of the enzyme activities, measured with different substrates under alteration of lysosomes, may be due to the heterogeneity of molecular forms of acid phosphatase.