Tret'iakov A V, Riazanov E M, Filov V A
Tsitologiia. 1982 Mar;24(3):307-10.
Heterogeneity of acid phosphatase in lysosomes of the rat's liver and the Zhaidel hepatoma was studied by the DEAE-cellulose chromatography. It is found that different substrates are hydrolyzed by different molecular forms of the enzyme. It is suggested that variability in the increase of the enzyme activities, measured with different substrates under alteration of lysosomes, may be due to the heterogeneity of molecular forms of acid phosphatase.
采用二乙氨基乙基纤维素色谱法研究了大鼠肝脏和ZD肝癌细胞溶酶体中酸性磷酸酶的异质性。结果发现，该酶的不同分子形式可水解不同的底物。研究表明，在溶酶体变化的情况下，用不同底物测定的酶活性增加的变异性可能是由于酸性磷酸酶分子形式的异质性所致。
