Ikinger U, Wurster K, Terwey B, Möhring K
Urology. 1982 May;19(5):525-8. doi: 10.1016/0090-4295(82)90611-2.
Malignant testicular tumor microcalcifications are being reported at an increasing rate. However, whether or not the detection of microcalcifications had any clinical significance has not been clarified. In the the present study testicular specimens from 92 patients (43 with malignant and 49 with nonmalignant testicular diseases) were examined postoperatively by mammographic technique. Microcalcifications were identified in 32 of the testicular tumor specimens (74 per cent), more frequently in teratomas (87 per cent) than in seminomas (60 per cent), and in 3 "burned-out" tumors. In contrast, only 8 of the benign testicular specimens showed microcalcifications (16 per cent). The arrangement of microcalcifications as well as the distinct pattern of distribution may further discriminate nonmalignant from malignant entities. Though the rate of detection and allocation of microcalcifications in malignant testicular tumors was a surprising finding, the general use of orchioradiography seems problematic because of the risk of potential damage to the germinal epithelium. In occult carcinoma, however, preoperative or orchioradiography may be justified.
恶性睾丸肿瘤微钙化的报道日益增多。然而，微钙化的检测是否具有临床意义尚未明确。在本研究中，对92例患者（43例患有恶性睾丸疾病，49例患有非恶性睾丸疾病）的睾丸标本术后采用乳腺X线摄影技术进行检查。在32例睾丸肿瘤标本中发现了微钙化（74%），畸胎瘤中微钙化的出现频率更高（87%），而精原细胞瘤中为60%，在3例“消退型”肿瘤中也有发现。相比之下，良性睾丸标本中只有8例显示有微钙化（16%）。微钙化的排列以及独特的分布模式可能进一步区分良性和恶性病变。虽然在恶性睾丸肿瘤中微钙化的检测率和分布情况是一个令人惊讶的发现，但由于存在对生精上皮造成潜在损害的风险，睾丸放射造影术的广泛应用似乎存在问题。然而，在隐匿性癌中，术前进行睾丸放射造影术可能是合理的。
