Father-son testicular malignancy. Does genetic anticipation occur?
作者信息
Raghavan D, Jelihovsky T, Fox R M
出版信息
Cancer. 1980 Mar 1;45(5):1005-9. doi: 10.1002/1097-0142(19800301)45:5<1005::aid-cncr2820450529>3.0.co;2-0.
Abstract
Testicular malignancy in a father and son is reported. The father had sequential bilateral seminomas while the son had embryonal cell carcinoma and seminoma. Reported cases of father-son testicular malignancy are reviewed and a predominance of seminomas in the fathers is apparent while the sons' tumors are highly malignant teratomas, choriocarcinomas and embryonal cell carcinomas. The possibility of genetic anticipation in father-son testicular malignancy is discussed.
摘要
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