[The cardiovascular risk profile of the long-term diabetic].

The long-term diabetic is in a considerable degree endangered by macroangiopathy. With a high probability their profile is influenced by the factors of cardiovascular endangering overweight (Broca-weight greater than or equal to 110%), hypertension (RR greater than or equal to 160/95 mm Hg), hypertriglyceridaemia (greater than or equal to 200 mg/dl), hypercholesterolaemia (greater than or equal to 260 mg/dl) and hyperuricaemia (greater than or equal to 6.5 mg/dl in male and greater than or equal to 6.0 mg/dl in female). Our analysis of the profile of the cardiovascular risk of 217 long-term diabetics with an average duration of the disease of 19.8 years and an average age of 60.2 years showed in comparison to normal persons an increased frequency of hypertension, hypertriglyceridaemia, hypercholesterolaemia and hyperuricaemia, whereas the weight did not differ from a normal population. Taking into consideration the same age structure the association of the examined 5 signs of risk is less narrow in the long-term diabetic than in the newly detected diabetic. With growing age the values of uric acid of the serum increase; in long-term diabetics their concentration surpasses that one of newly detected diabetic patients. From the point of view of preventive medicine factors of cardiovascular risk must be recognized already in the newly detected diabetes of type I or II as well as in disturbed glucose tolerance and, as far as possible, be influenced in the sense of an improvement of the profile of the risk.