Schneider H, Pastow A
Z Gesamte Inn Med. 1982 May 15;37(10):295-9.
Of 250 diabetics with a duration of the disease between 15 and 54 years the relations between the renal function and the cardiovascular risk profile were examined. The clearly increased serum creatinine values the frequency of persons with overweight was lower than in diabetics with very favourable creatinine levels. The increasing concentration of the serum led to an increase of the frequency of hyperuricaemia, whereas the frequencies of hypertension hypertriglyceridaemia and hypercholesterolaemia did not show any significant changes. The habits of smoking of long-term diabetics with and without renal insufficiency did not differ from each other qualitatively. Particularly after the 50th year of age long-term diabetics more frequently had diabetic blood-relatives than newly detected diabetic patients of the same age. Patients with familial occurrence of diabetes (relatives of 1st degree) in comparison to diabetics without known diabetic relatives showed an identical cardiovascular risk profile, so that there is no influence of the heredity of diabetes on the formation of the non-diabetic sizes of influence of the metabolic syndrome.
在250名病程在15至54年之间的糖尿病患者中，研究了肾功能与心血管风险状况之间的关系。血清肌酐值明显升高时，超重者的频率低于肌酐水平非常良好的糖尿病患者。血清浓度的升高导致高尿酸血症频率增加，而高血压、高甘油三酯血症和高胆固醇血症的频率未显示任何显著变化。有和没有肾功能不全的长期糖尿病患者的吸烟习惯在质量上没有差异。特别是在50岁以后，长期糖尿病患者比同年龄新发现的糖尿病患者更常有糖尿病血亲。与没有已知糖尿病亲属的糖尿病患者相比，有家族性糖尿病发生（一级亲属）的患者表现出相同的心血管风险状况，因此糖尿病遗传对代谢综合征非糖尿病影响因素的形成没有影响。
