小型猪十二指肠胰腺反馈的存在及胆汁可能产生的干扰。
Presence of duodenopancreatic feedback in minipigs and possible interference from the bile.
作者信息
Vantini I, Pederzoli P, Maffezzoli G F, Brocco G, Cavallini G, Pilon T, Benini P, Ederle A, Piubello W, Benini L, Ferrini S, Marchiori N, Scuro L A
出版信息
Am J Gastroenterol. 1982 Mar;77(3):154-7.
In two minipigs chronic pancreatic and duodenal fistulas, which allowed the diversion and the intestinal replacement of pancreatic secretion, were prepared. In a third minipig a chronic biliary fistula was also prepared so the bile secretion could be fed back into the intestine through a duodenal catheter. In these animals a chronic gastric fistula was made so gastric secretion could also be collected. Diversion-replacement of pure pancreatic juice and of bile were carried out in the fasting state. This study confirms the presence of a feedback regulatory mechanism in exocrine pancreatic secretion in the pig. Moreover, it suggests that bile can interfere with this phenomenon.
制备了两只小型猪的慢性胰瘘和十二指肠瘘，用于实现胰液的转流和肠道替代。还为第三只小型猪制备了慢性胆瘘，以便胆汁分泌可通过十二指肠导管反馈回肠道。在这些动物身上制作了慢性胃瘘，以便收集胃液。在禁食状态下进行纯胰液和胆汁的转流-替代。本研究证实了猪外分泌性胰腺分泌中存在反馈调节机制。此外，还表明胆汁可干扰这一现象。
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