Attia W M, Shams A H, Ali M K, Clark H W, Brown T M, Bellanti J A
Ann Allergy. 1982 May;48(5):279-82.
The polymorphonuclear cells (PMN's) of 20 patients with rheumatoid arthritis (RA) were analyzed for endocytic ability and metabolic capacity and were compared to those from a healthy control group over short intervals. The results of these studies indicate that the phagocytic activity (PA) and the nitroblue tetrazolium (NBT) dye reduction were significantly decreased in RA patients after 30 minutes of incubation. The rheumatoid patients showed a higher percentage of band cells and hypersegmented nuclei of their peripheral blood PMN's (PB-PMN's). No correlation was found between neutrophil functions and other parameters of the rheumatoid disease activity.
对20例类风湿关节炎（RA）患者的多形核细胞（PMN）进行了内吞能力和代谢能力分析，并在短时间内与健康对照组进行了比较。这些研究结果表明，孵育30分钟后，RA患者的吞噬活性（PA）和硝基蓝四氮唑（NBT）染料还原能力显著降低。类风湿患者外周血PMN（PB-PMN）的杆状核细胞和核分叶过多的比例较高。未发现中性粒细胞功能与类风湿疾病活动的其他参数之间存在相关性。
