Carniol P J, Fried M P
Ann Otol Rhinol Laryngol. 1982 Mar-Apr;91(2 Pt 1):152-5. doi: 10.1177/000348948209100206.
From 1965-1978 over 2,700 patients were admitted to the Massachusetts Eye and Ear Infirmary or the Massachusetts General Hospital with carcinoma of the oropharynx, larynx or nasopharynx; only 36 of these patients were less than 40 years of age. Twelve patients had oropharyngeal carcinoma, 13 patients had laryngeal or hypopharyngeal carcinoma, and 11 patients had nasopharyngeal carcinoma. Analysis of these patients indicates an increased incidence of head and neck cancer in younger females. In patients less than age 31 there was no significant social history which contributed to early onset of disease. The younger patients with nasopharyngeal carcinoma survived longer than patients of all ages with comparable neoplasms. The survival of patients with oropharyngeal, laryngeal and hypopharyngeal carcinoma is comparable to survival in patients of all ages with similar lesions.
1965年至1978年期间，超过2700例口咽、喉或鼻咽癌患者被收治于马萨诸塞州眼耳医院或马萨诸塞州总医院；其中只有36例患者年龄小于40岁。12例患者患有口咽癌，13例患者患有喉或下咽癌，11例患者患有鼻咽癌。对这些患者的分析表明，年轻女性头颈癌的发病率有所增加。在年龄小于31岁的患者中，没有明显的社会病史导致疾病早发。患有鼻咽癌的年轻患者比所有年龄段患有类似肿瘤的患者存活时间更长。口咽、喉和下咽癌患者的生存率与所有年龄段患有类似病变的患者的生存率相当。
