Cooke T
Ann R Coll Surg Engl. 1982 May;64(3):165-70.
The analysis of receptors for oestrogen in early cancer of the breast may be used to predict prognosis. The presence or absence of oestrogen receptors is independent of menstrual status, the stage of the patient's disease, and the histological grade of the tumour. Therefore combination with other prognostic factors gives a more accurate assessment of an individual patient's outlook. In the study described prognostic subgroups were determined from tumour axillary lymph node histology and oestrogen receptor status. The clinical application of these findings is discussed.
对早期乳腺癌雌激素受体的分析可用于预测预后。雌激素受体的有无与月经状态、患者疾病分期及肿瘤组织学分级无关。因此,将其与其他预后因素相结合能更准确地评估个体患者的前景。在所描述的研究中,根据肿瘤腋窝淋巴结组织学和雌激素受体状态确定了预后亚组。并对这些发现的临床应用进行了讨论。