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庆大霉素不螯合钙。

Gentamicin does not chelate calcium.

作者信息

Kohlhepp S J, Plant S B, McCarron D A, Gilbert D N

出版信息

Antimicrob Agents Chemother. 1982 Apr;21(4):668-9. doi: 10.1128/AAC.21.4.668.

Abstract

The influence of increasing gentamicin concentrations on ionized calcium concentration was determined in pH-controlled, phosphate-buffered saline and normal human serum with an ion-specific calcium electrode. No evidence of calcium chelation was found.

摘要

使用离子特异性钙电极,在pH值受控的磷酸盐缓冲盐水和正常人血清中,测定了庆大霉素浓度增加对离子钙浓度的影响。未发现钙螯合的证据。

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本文引用的文献

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Metal chelates of streptomycin.链霉素的金属螯合物
J Am Pharm Assoc Am Pharm Assoc. 1955 May;44(5):261-3. doi: 10.1002/jps.3030440503.
4
Relation of aerobiosis and ionic strength to the uptake of dihydrostreptomycin in Escherichia coli.
Biochim Biophys Acta. 1980 Nov 5;593(1):1-10. doi: 10.1016/0005-2728(80)90002-x.
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A new method for determining micro quantities of calcium in biological materials.
Anal Biochem. 1967 Jul;20(1):155-66. doi: 10.1016/0003-2697(67)90273-4.

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