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轻度头部损伤时脑脊液中的细胞学、乳酸脱氢酶和肌酸激酶(作者译)

[Cytology, lactate dehydrogenase, and creatine kinase in CSF in mild head injuries (author's transl)].

作者信息

Weitbrecht W U, Weigel K, Stengele G

出版信息

Arch Psychiatr Nervenkr (1970). 1978 Aug 22;225(4):349-57. doi: 10.1007/BF00343306.

Abstract

Cytology, lactate dehydrogenase, and creatine kinase in cerebrospinal fluid were investigated 6-72h after mild head injuries in 59 patients aged 16-49 years. Significant differences were not found in creatine kinase. Lactate dehydrogenase, however, was significantly more elevated in mild cerebral contusions compared with concussions 24h after head injury. Monocytoid reaction in cerebrospinal fluid was significantly more distinct in mild contusions compared with concussions 24h after impact. Large phagocytes were rarely found in concussions and were not traceable 48h after impact. Large phagocytes, however, were found in 50-55% of the mild contusions 48-72h after head injury. Siderophages were found only in contusions (16.5-35%), 48-72h after impact). The optimal time for lumbar punction is 24h after head injury.

摘要

对59例年龄在16至49岁的轻度颅脑损伤患者,在受伤后6至72小时检测其脑脊液中的细胞学、乳酸脱氢酶和肌酸激酶。肌酸激酶未发现显著差异。然而,与脑震荡相比,轻度脑挫裂伤患者在受伤后24小时乳酸脱氢酶显著升高。与脑震荡相比,受伤后24小时轻度脑挫裂伤患者脑脊液中的单核细胞样反应明显更显著。脑震荡中很少发现大吞噬细胞,受伤后48小时也无法追踪到。然而,在头部受伤后48至72小时,50%至55%的轻度脑挫裂伤患者中发现了大吞噬细胞。含铁吞噬细胞仅在受伤后48至72小时的脑挫裂伤中发现(16.5%至35%)。腰椎穿刺的最佳时间是头部受伤后24小时。

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