Flórez G, Cabeza A, Gonzalez J M, Garcia J, Ucar S
Acta Neurochir (Wien). 1976;35(1-3):3-13. doi: 10.1007/BF01405928.
We studied simultaneously in serum (S) and CSF (L) the enzyme activities of GOT, GPT, LDH, ICDH, MDH, ALD, and CPK in 28 patients with head injuries divided into three groups according to the severity of the trauma. We found a correlation between severity of brain lesion and enzyme activity. The best correlation was found for SGOT, SCPK, LGOT, LLDH, LMDH and LCPK. We do not believe that enzyme activity is of prognostic value. We think that further studies should be made of the specific isoenzymes of the Central Nervous System.
我们同时研究了28例头部受伤患者血清（S）和脑脊液（L）中的谷草转氨酶（GOT）、谷丙转氨酶（GPT）、乳酸脱氢酶（LDH）、异柠檬酸脱氢酶（ICDH）、苹果酸脱氢酶（MDH）、醛缩酶（ALD）和肌酸磷酸激酶（CPK）的酶活性。这些患者根据创伤严重程度分为三组。我们发现脑损伤严重程度与酶活性之间存在相关性。谷草转氨酶（SGOT）、血清肌酸磷酸激酶（SCPK）、脑脊液谷草转氨酶（LGOT）、脑脊液乳酸脱氢酶（LLDH）、脑脊液苹果酸脱氢酶（LMDH）和脑脊液肌酸磷酸激酶（LCPK）的相关性最佳。我们认为酶活性没有预后价值。我们认为应该对中枢神经系统的特异性同工酶进行进一步研究。
