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Long term maintenance and induction of cytochrome P-450 in rat liver cell culture.

作者信息

Paine A J, Hockin L J, Allen C M

出版信息

Biochem Pharmacol. 1982 Mar 15;31(6):1175-8. doi: 10.1016/0006-2952(82)90364-1.

DOI:10.1016/0006-2952(82)90364-1
PMID:7082371
Abstract
摘要

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Long term maintenance and induction of cytochrome P-450 in rat liver cell culture.大鼠肝细胞培养中细胞色素P - 450的长期维持与诱导
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Expression of cytochromes P-450 in rat hepatoma cells. Analysis by monoclonal antibodies specific for cytochromes P-450 from rat liver induced by 3-methylcholanthrene or phenobarbital.大鼠肝癌细胞中细胞色素P-450的表达。用针对由3-甲基胆蒽或苯巴比妥诱导的大鼠肝脏细胞色素P-450的单克隆抗体进行分析。
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Eur J Biochem. 1981 May;116(1):67-72. doi: 10.1111/j.1432-1033.1981.tb05301.x.

引用本文的文献

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Activation of Cyp1a1 and Cyp1a2 genes in adult mouse hepatocytes in primary culture.原代培养的成年小鼠肝细胞中Cyp1a1和Cyp1a2基因的激活。
Jpn J Cancer Res. 1993 Mar;84(3):272-8. doi: 10.1111/j.1349-7006.1993.tb02867.x.
2
Cryopreservation and long-term storage of primary rat hepatocytes: effects on substrate-specific cytochrome P450-dependent activities and unscheduled DNA synthesis.原代大鼠肝细胞的冷冻保存和长期储存:对底物特异性细胞色素P450依赖性活性和非程序性DNA合成的影响。
Cell Biol Toxicol. 1993 Oct-Dec;9(4):345-57. doi: 10.1007/BF00754463.
3
Sex differences in the biotransformation of 2-acetylaminofluorene in cultured rat hepatocytes.
培养的大鼠肝细胞中2-乙酰氨基芴生物转化的性别差异。
Cell Biol Toxicol. 1986 Jun;2(2):271-81. doi: 10.1007/BF00122695.
4
Drug metabolizing enzymes in rat hepatocytes co-cultured with cell lines.
In Vitro Cell Dev Biol. 1990 Nov;26(11):1057-62. doi: 10.1007/BF02624440.
5
Phenobarbital induction of cytochrome P-450 gene expression.苯巴比妥对细胞色素P-450基因表达的诱导作用。
Biochem J. 1992 Feb 1;281 ( Pt 3)(Pt 3):577-92. doi: 10.1042/bj2810577.
6
Cell culture systems and in vitro toxicity testing. Technical report no. 4 of the Johns Hopkins Center for Alternatives to Animal Testing (CAAT): technical workshop of June 13-15, 1990.细胞培养系统与体外毒性测试。约翰霍普金斯大学动物实验替代方法中心(CAAT)技术报告第4号:1990年6月13 - 15日技术研讨会。
Cytotechnology. 1992;8(2):129-76.