Bentley-Phillips C B, Cooper R C, Hallett A F
Br J Dermatol. 1982 Jun;106(6):687-95. doi: 10.1111/j.1365-2133.1982.tb11684.x.
A 50-year-old man with recurrent life-threatening sepsis and a cutaneous condition resembling pyoderma gangrenosum, was found to have a defect of neutrophil phagocytic function. Phagocytosis could be enhanced by corticosteroids, both in vitro in a dose-dependent manner, and in vivo, when it was accompanied by rapid clinical improvement. Studies with steroid hormones and immuno-stimulatory drugs are described.
一名50岁男性，反复发生危及生命的败血症，并有类似坏疽性脓皮病的皮肤状况，被发现存在中性粒细胞吞噬功能缺陷。在体外，皮质类固醇能以剂量依赖的方式增强吞噬作用；在体内，当给予皮质类固醇后临床症状迅速改善时，吞噬作用也会增强。文中描述了关于类固醇激素和免疫刺激药物的研究。
