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[中脑中央灰质刺激对血流动力学伤害性反应的影响]

[Effect of stimulation of the central gray substance of the midbrain on hemodynamic nociceptive reactions].

作者信息

Zaĭtsev A A, Dmitriev A V, Ignatov Iu D

出版信息

Biull Eksp Biol Med. 1982 Apr;93(4):52-4.

PMID:7082802
Abstract

Experiments on unrestrained rats were made to study the influence of central gray matter of the midbrain, whose activation evokes analgesia, on hemodynamic manifestations of pain reactions under tooth pulp irritation. Electrical stimulation of the brain "analgetic areas" that does not change the animals' behavior or vegetative indices at rest decreased or abolished nociceptive arterial pressure reactions and tachycardia. Possible mechanisms of central gray matter of the midbrain influence on the pain-evoked vegetative reactions are discussed.

摘要

对自由活动的大鼠进行实验,以研究中脑中央灰质(其激活可诱发镇痛)对牙髓刺激下疼痛反应的血流动力学表现的影响。对大脑“镇痛区”进行电刺激,在静息状态下不改变动物行为或自主指标,可减少或消除伤害性动脉血压反应和心动过速。文中讨论了中脑中央灰质影响疼痛诱发的自主反应的可能机制。

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