Kim Y H, Reiner L
Cancer. 1982 Jul 1;50(1):102-6. doi: 10.1002/1097-0142(19820701)50:1<102::aid-cncr2820500119>3.0.co;2-7.
Eleven benign lipogenic tumors comprising ten ordinary lipomas and one fibroblastic lipoma were studied by light and electron microscopy. The former, which contained only a few inconspicuous septa, were composed of univacuolar mature adipocytes. No young forms of adipocytic differentiation were seen reflecting the slow growth of the ordinary lipomas. Small spindle cells accompanying capillaries located in the triangular confluence of the adipocytes are thought to be potential precursors of adipocytes. By contrast, the fibroblastic lipoma contained many younger forms which closely resembled those seen during maturation of normal adipose tissue. These younger forms are located in and about prominent trabeculae which therefore are considered to constitute active growth centers.
对11个良性脂肪生成性肿瘤进行了光镜和电镜研究,其中包括10个普通脂肪瘤和1个纤维母细胞性脂肪瘤。前者仅含有少量不明显的间隔,由单泡状成熟脂肪细胞组成。未见脂肪细胞分化的年轻形式,这反映了普通脂肪瘤生长缓慢。位于脂肪细胞三角形汇合处并伴有毛细血管的小梭形细胞被认为是脂肪细胞的潜在前体。相比之下,纤维母细胞性脂肪瘤含有许多更年轻的形式,与正常脂肪组织成熟过程中所见的非常相似。这些更年轻的形式位于突出的小梁内及周围,因此被认为构成活跃的生长中心。