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颤抖小鼠和跳跃小鼠坐骨神经髓磷脂中的蛋白质

Proteins from sciatic-nerve myelin in quaking and jimpy mice.

作者信息

Matthieu J M

出版信息

Biochem J. 1978 Sep 1;173(3):989-91. doi: 10.1042/bj1730989.

DOI:10.1042/bj1730989
PMID:708386
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1185869/
Abstract

Myelin from two neurological mutants in mice was isolated from sciatic nerves and its protein composition analysed. In Quaking mice, two intrinsic myelin proteins P1 and P2 were drastically decreased, whereas the major myelin protein P0 was unaffected. A normal protein composition was found in sciatic myelin from Jimpy mice.

摘要

从两只小鼠神经突变体的坐骨神经中分离出髓磷脂，并分析其蛋白质组成。在颤抖小鼠中，两种内在髓磷脂蛋白P1和P2大幅减少，而主要髓磷脂蛋白P0未受影响。在迟钝小鼠的坐骨髓磷脂中发现了正常的蛋白质组成。

相似文献

1
Proteins from sciatic-nerve myelin in quaking and jimpy mice.颤抖小鼠和跳跃小鼠坐骨神经髓磷脂中的蛋白质
Biochem J. 1978 Sep 1;173(3):989-91. doi: 10.1042/bj1730989.
2
Order-disorder phenomena in myelinated nerve sheaths. VI. The effects of quaking, jimpy and shiverer mutations: an X-ray scattering study of mouse sciatic and optic nerves.有髓神经鞘中的有序-无序现象。VI. 颤抖、跳跃和颤抖者突变的影响：小鼠坐骨神经和视神经的X射线散射研究。
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Regional distribution of myelin basic protein in the central nervous system of quaking, jimpy, and normal mice during development and aging.发育和衰老过程中，震颤小鼠、跳跃小鼠及正常小鼠中枢神经系统中髓鞘碱性蛋白的区域分布。
J Neurosci Res. 1981;6(3):303-13. doi: 10.1002/jnr.490060305.

引用本文的文献

1
Cellular and molecular aspects of myelin protein gene expression.髓磷脂蛋白基因表达的细胞与分子层面
Mol Neurobiol. 1988 Spring;2(1):41-89. doi: 10.1007/BF02935632.

本文引用的文献

1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
Hypomyelination in the quaking mouse. A model for the analysis of disturbed myelin formation.颤抖小鼠的髓鞘形成不全。用于分析髓鞘形成紊乱的模型。
J Neuropathol Exp Neurol. 1970 Oct;29(4):507-23. doi: 10.1097/00005072-197010000-00001.
3
Quaking mouse: isolation and characterization of myelin protein.颤抖小鼠：髓鞘蛋白的分离与特性分析
J Neurochem. 1971 Nov;18(11):2119-28. doi: 10.1111/j.1471-4159.1971.tb05070.x.
4
Abnormality in sphingolipid fatty acids from sciatic nerve and brain of Quaking mice.颤抖小鼠坐骨神经和大脑中鞘脂脂肪酸的异常。
J Neurochem. 1971 Jul;18(7):1365-8. doi: 10.1111/j.1471-4159.1971.tb00240.x.
5
Dysmyelination in "quaking" mouse. Electron microscopic study.“颤抖”小鼠的髓鞘形成异常。电子显微镜研究。
J Neuropathol Exp Neurol. 1972 Apr;31(2):352-69. doi: 10.1097/00005072-197204000-00010.
6
A major myelin glycoprotein of sciatic nerve.坐骨神经的一种主要髓磷脂糖蛋白。
J Neurochem. 1973 Sep;21(3):717-9. doi: 10.1111/j.1471-4159.1973.tb06019.x.
7
Evidence that the major protein in rat sciatic nerve myelin is a glycoprotein.大鼠坐骨神经髓鞘中的主要蛋白质是一种糖蛋白的证据。
J Neurochem. 1973 Aug;21(2):329-34. doi: 10.1111/j.1471-4159.1973.tb04253.x.
8
Protein composition of myelin of the peripheral nervous system.外周神经系统髓磷脂的蛋白质组成。
J Neurochem. 1973 Apr;20(4):1207-16. doi: 10.1111/j.1471-4159.1973.tb00089.x.
9
Biosynthesis of psychosine and levels of cerebrosides in the central and peripheral nervous systems of quaking mice.颤抖小鼠中枢和外周神经系统中鞘氨醇半乳糖苷的生物合成及脑苷脂水平
J Neurochem. 1973 Apr;20(4):1131-41. doi: 10.1111/j.1471-4159.1973.tb00083.x.
10
The proposed amino acid sequence of the P1 protein of rabbit sciatic nerve myelin.兔坐骨神经髓鞘P1蛋白的推测氨基酸序列。
Arch Biochem Biophys. 1972 Dec;153(2):590-8. doi: 10.1016/0003-9861(72)90377-3.