Pryse-Phillips W, Jardine F, Bursey F
Epilepsia. 1982 Jun;23(3):269-74. doi: 10.1111/j.1528-1157.1982.tb06191.x.
Fifty patients with epilepsy were randomly divided into three groups and given, respectively, oral information about the nature, purpose, appearances, functions, and unwanted effects of their medications at an initial interview; the same information supplemented by its presentation in written form for the patient to take home; and the same information by telephone contact only. Compliance with anticonvulsant therapy was assessed by interview and by drug levels. The amount of knowledge retained and the drug levels were measured again 4 weeks later. While no increase in serum levels could be detected over the mean values in the first interview, no reduction in levels could be documented either, although the drug information sheets had listed both the minor and the more serious unwanted effects of the drugs. The patients' information scores improved significantly in all three groups, but the combination of data presented at interview both orally and in written form was markedly superior to the other methods.
50名癫痫患者被随机分为三组，在初次面谈时分别给予关于其药物的性质、用途、外观、功能及不良反应的口头信息；相同信息并辅以书面形式供患者带回家；以及仅通过电话联系提供相同信息。通过面谈和药物水平评估对抗惊厥治疗的依从性。4周后再次测量知识保留量和药物水平。虽然在初次面谈中未检测到血清水平相对于平均值有所升高，但也没有记录到水平降低，尽管药物信息单列出了药物的轻微和较严重的不良反应。所有三组患者的信息得分均显著提高，但面谈时以口头和书面形式呈现数据的组合明显优于其他方法。
