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3H-2-亚氨基-7-甲基-4-氧代吡啶并[3,2-e]-1,3-噻嗪-5-羧酸甲酯新衍生物的合成与性质研究

Investigations on the synthesis and properties of new derivatives of methyl 3H-2-imino-7-methyl-4-oxopyrido [3,2-e]-1,3-thiazine-5-carboxylate.

作者信息

Zawisza T, Siwińska B, Sladowska H, Jakóbiec T

出版信息

Farmaco Sci. 1982 Apr;37(4):266-74.

PMID:7084448
Abstract

Condensation of dimethyl 2-chloro-6-methylpyridine-3,4-dicarboxylate with thiourea and its N-substituted derivatives is described. It has been found that depending on the kind of substituents in the starting thiourea derivatives, pyrido [3,2-e]-1,3-thiazine or pyrido [2,3-d] pyrimidine derivatives were formed.

摘要

描述了2-氯-6-甲基吡啶-3,4-二甲酸二甲酯与硫脲及其N-取代衍生物的缩合反应。已发现，根据起始硫脲衍生物中取代基的种类，会形成吡啶并[3,2-e]-1,3-噻嗪或吡啶并[2,3-d]嘧啶衍生物。

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1
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