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吡啶并[3,2 - e]-1,3 -噻嗪并[3,2 - a]-均三嗪新衍生物的合成与性质研究

Investigations on the synthesis and properties of new derivatives of pyrido[3,2-e]-1,3-thiazino[3,2-a]-s-triazine.

作者信息

Sladowska H, Bartoszko-Malik A, Zawisza T

出版信息

Farmaco Sci. 1985 Jan;40(1):65-72.

PMID:3979547
Abstract

It has been found that the condensation of esters of 3H-2-imino-7-methyl-4-oxopyrido[3,2-e]-1,3-thiazine-5- and -6-carboxylic acids (I, II) with formaldehyde and primary amines affords the corresponding derivatives of a new heterocyclic system pyrido[3,2-e]-1,3-thiazino [3,2-a]-s-triazine (IX-XXIV).

摘要

已发现，3H-2-亚氨基-7-甲基-4-氧代吡啶并[3,2-e]-1,3-噻嗪-5-和-6-羧酸（I，II）的酯与甲醛和伯胺缩合可得到新杂环体系吡啶并[3,2-e]-1,3-噻嗪并[3,2-a]-s-三嗪（IX-XXIV）的相应衍生物。

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