Daly D C, Tohan N, Doney T J, Maslar I A, Riddick D H
Fertil Steril. 1982 Jun;37(6):786-91. doi: 10.1016/s0015-0282(16)46339-9.
The effectiveness of the endometrial biopsy in diagnosing luteal phase defects as a cause of infertility depends upon the accurate determination of a histologic date based on the morphologic features of tissue. The criteria--edema, predecidual reaction, stromal mitosis, and lymphocytic-leukocytic infiltrate--used to interpret such biopsies were based on changes occurring in the normal ideal menstrual cycle. The present study examines the criteria used for dating endometrium as applied to endometrial biopsies for luteal phase deficiency. It was determined that one of these criteria, lymphocytic and leukocytic infiltration, correlated with subsequent onset of menses and not with the other indications of histologic maturity during the late secretory phase.
子宫内膜活检用于诊断黄体期缺陷所致不孕症的有效性，取决于基于组织形态学特征准确确定组织学日期。用于解读此类活检的标准——水肿、蜕膜前期反应、基质有丝分裂以及淋巴细胞-白细胞浸润——是基于正常理想月经周期中发生的变化制定的。本研究探讨了用于子宫内膜日期判定的标准在黄体期缺陷子宫内膜活检中的应用情况。研究发现，这些标准中的一项，即淋巴细胞和白细胞浸润，与随后的月经来潮相关，而与分泌晚期组织学成熟的其他指标无关。
