Wolfson D M, Sachar D B, Cohen A, Goldberg J, Styczynski R, Greenstein A J, Gelernt I M, Janowitz H D
Gastroenterology. 1982 Aug;83(2):405-9.
Previous studies have reached disparate conclusions on the issue of whether or not granulomas confer any protection against recurrence of Crohn's disease after operation. In an attempt to resolve this controversy, we have examined postoperative recurrence rates in 102 patients with Crohn's disease. There were no differences in cumulative postoperative recurrence-free survival between the 53 patients with granulomas present in the resected specimens and the 49 patients without granulomas. It was concluded that the presence of granulomas in resected specimens of Crohn's disease exerts no independent influence on the rate of postoperative recurrence.
先前的研究在肉芽肿是否对克罗恩病术后复发具有任何保护作用这一问题上得出了不同的结论。为了解决这一争议，我们检查了102例克罗恩病患者的术后复发率。在切除标本中存在肉芽肿的53例患者与无肉芽肿的49例患者之间，术后累积无复发生存率没有差异。得出的结论是，克罗恩病切除标本中肉芽肿的存在对术后复发率没有独立影响。
