Doll D C
Hum Pathol. 1982 Jul;13(7):671-2. doi: 10.1016/s0046-8177(82)80013-0.
Spur-cell anemia is characterized by the presence of an abnormally shaped erythrocyte, the acanthocyte. Platelets from two patients with spur-cell anemia were studied by scanning electron microscopy to determine whether there were any abnormalities of platelet shape. In both cases, irregularly distributed bulbous-like projections were observed on the platelet surface membrane. These observations suggest that platelets from patients with spur-cell anemia have an abnormal surface morphology.
棘状细胞贫血的特征是存在异常形状的红细胞,即棘状红细胞。通过扫描电子显微镜研究了两名棘状细胞贫血患者的血小板,以确定血小板形状是否存在任何异常。在这两个病例中,均在血小板表面膜上观察到分布不规则的球状突起。这些观察结果表明,棘状细胞贫血患者的血小板具有异常的表面形态。