Chitale A A, Sterling R K, Post A B, Silver B J, Mulligan D C, Schulak J A
Department of Medicine, University Hospitals of Cleveland, Case Western Reserve University, Ohio, USA.
Transplantation. 1998 Apr 15;65(7):993-5. doi: 10.1097/00007890-199804150-00021.
Spur cell anemia is an acquired hemolytic anemia, characterized by an increased percentage of abnormally shaped erythrocytes that are known as acanthocytes. The erythrocytes have numerous spicules irregularly distributed over the cell surface. Spur cell anemia has been described to occur in several conditions, including cirrhosis. We present an unusual case of a young patient with hemochromatosis, alcohol abuse, decompensated cirrhosis, and spur cell anemia who had a spontaneous resolution of the spur cell anemia after orthotopic liver transplantation. This finding suggests that the diseased liver may contribute to transformation of the erythrocyte to the spur cell.
棘状细胞贫血是一种获得性溶血性贫血，其特征是异常形状的红细胞（即棘状红细胞）的百分比增加。这些红细胞有许多不规则分布在细胞表面的刺突。棘状细胞贫血已被描述为在包括肝硬化在内的几种情况下发生。我们报告了一例不寻常的病例，一名患有血色素沉着症、酗酒、失代偿性肝硬化和棘状细胞贫血的年轻患者，在原位肝移植后棘状细胞贫血自发缓解。这一发现表明，患病的肝脏可能促使红细胞转变为棘状细胞。
