常规粪便标本中的艰难梭菌和细胞毒素
Clostridium difficile and cytotoxin in routine faecal specimens.
作者信息
Nash J Q, Chattopadhyay B, Honeycombe J, Tabaqchali S
出版信息
J Clin Pathol. 1982 May;35(5):561-5. doi: 10.1136/jcp.35.5.561.
Abstract
Over a five-month period 1239 unselected, routine faecal specimens from 856 patients were examined for Clostridium difficile. One hundred specimens representing 69 patients were culture-positive. Toxin was detected in the stool of ten. During the study period, there were 41 Salmonella, 12 Campylobacter and 9 Shigella infections. C difficile was isolated together with Salmonella from 12 patients. No patient required specific treatment for C difficile infection. The significance of these findings is discussed.
摘要
在五个月的时间里，对来自856名患者的1239份未经筛选的常规粪便标本进行了艰难梭菌检测。代表69名患者的100份标本培养呈阳性。在10人的粪便中检测到毒素。在研究期间，有41例沙门氏菌感染、12例弯曲杆菌感染和9例志贺氏菌感染。从12名患者中分离出艰难梭菌和沙门氏菌。没有患者因艰难梭菌感染而需要特殊治疗。讨论了这些发现的意义。
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本文引用的文献
1
Faecal toxin and severity of antibiotic-associated pseudomembranous colitis.粪便毒素与抗生素相关性假膜性结肠炎的严重程度
J Clin Pathol. 1981 May;34(5):548-51. doi: 10.1136/jcp.34.5.548.
2
Isolation rates and toxigenic potential of Clostridium difficile isolates from various patient populations.来自不同患者群体的艰难梭菌分离株的分离率和产毒潜力。
Gastroenterology. 1981 Jul;81(1):5-9.
3
Clostridium difficile in relation to enteric bacterial pathogens.艰难梭菌与肠道细菌病原体的关系。
J Clin Microbiol. 1980 Sep;12(3):297-300. doi: 10.1128/jcm.12.3.297-300.1980.
4
Antibiotic and pseudomembranous colitis.
J Antimicrob Chemother. 1981 Jun;7 Suppl A:53-65. doi: 10.1093/jac/7.suppl_a.53.
5
Bacterial interference between Clostridium difficile and normal fecal flora.艰难梭菌与正常粪便菌群之间的细菌干扰。
J Infect Dis. 1981 Mar;143(3):470-5. doi: 10.1093/infdis/143.3.470.
6
Relapsing pseudomembranous colitis associated with cancer chemotherapy.与癌症化疗相关的复发性假膜性结肠炎
J Infect Dis. 1981 Jun;143(6):865. doi: 10.1093/infdis/143.6.865.
7
Clostridium difficile associated diarrhoea: a role in inflammatory bowel disease?艰难梭菌相关性腹泻：在炎症性肠病中起作用？
Lancet. 1980 Feb 23;1(8165):383-4. doi: 10.1016/s0140-6736(80)90940-x.
8
Therapeutic implications of Clostridium difficile toxin during relapse of chronic inflammatory bowel disease.艰难梭菌毒素在慢性炎症性肠病复发过程中的治疗意义
Lancet. 1980 Feb 23;1(8165):381-3. doi: 10.1016/s0140-6736(80)90939-3.
9
Undescribed toxin in pseudomembranous colitis.伪膜性结肠炎中未描述的毒素。
Br Med J. 1977 May 14;1(6071):1246-8. doi: 10.1136/bmj.1.6071.1246.
10
Identification of Clostridium difficile as a cause of pseudomembranous colitis.艰难梭菌被鉴定为伪膜性结肠炎的病因。
Br Med J. 1978 Mar 18;1(6114):695. doi: 10.1136/bmj.1.6114.695.
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