Daly C H
J Invest Dermatol. 1982 Jul;79 Suppl 1:17s-20s. doi: 10.1111/1523-1747.ep12544620.
Data obtained from a wide variety of test methods both in vitro and in vivo and histological studies of stressed skin have led to an understanding of the mechanical properties of the dermis and the relation of these properties to the structure of the collagen and elastin fiber networks of the dermis. The mechanical properties are found to be well adapted to the mechanical function of the dermis. The viscoelastic nature of the skin shows that a simple structural model based only on collagen and elastin is not adequate for a full understanding of this tissue. The role of proteoglycans in bonding collagen fibrils into large fibers and in connecting these fibers into the fibrous net of the dermis is not well understood. Mechanical testing can yield information on the nature of bonds at this level of structure.
通过多种体外和体内测试方法以及对应激皮肤的组织学研究获得的数据，使人们对真皮的力学性能以及这些性能与真皮中胶原蛋白和弹性纤维网络结构的关系有了认识。研究发现，这些力学性能与真皮的机械功能非常匹配。皮肤的粘弹性表明，仅基于胶原蛋白和弹性蛋白的简单结构模型不足以全面理解该组织。蛋白聚糖在将胶原原纤维结合成大纤维以及将这些纤维连接到真皮纤维网中的作用尚未得到充分理解。力学测试可以提供有关该结构水平上键的性质的信息。
