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Apyrogenic, adjuvant-active N-acetylmuramyl-dipeptides.

作者信息

Lefrancier P, Derrien M, Jamet X, Choay J, Lederer E, Audibert F, Parant M, Parant F, Chedid L

出版信息

J Med Chem. 1982 Jan;25(1):87-90. doi: 10.1021/jm00343a018.

DOI:10.1021/jm00343a018
PMID:7086827
Abstract
摘要

相似文献

1
Apyrogenic, adjuvant-active N-acetylmuramyl-dipeptides.无热原性、佐剂活性的N-乙酰胞壁酰二肽。
J Med Chem. 1982 Jan;25(1):87-90. doi: 10.1021/jm00343a018.
2
Chemical synthesis and adjuvant activity of N-acetylmuramyl-L-alanyl-D-isoglutamine (MDP) analogs 1, 2.N-乙酰胞壁酰-L-丙氨酰-D-异谷氨酰胺（MDP）类似物1、2的化学合成及佐剂活性
Chem Pharm Bull (Tokyo). 1981 Jun;29(6):1644-54. doi: 10.1248/cpb.29.1644.
3
Synthesis of carbohydrate analogs (positional, configurational, and optical) of n-acetylmuramoyl-L-alanyl-D-isoglutamine, and their immunoadjuvant activities.N-乙酰胞壁酰-L-丙氨酰-D-异谷氨酰胺的碳水化合物类似物（位置、构型和旋光）的合成及其免疫佐剂活性。
Carbohydr Res. 1981 Aug 1;94(2):143-63. doi: 10.1016/s0008-6215(00)80713-2.
4
Synthesis of immunologically active muramyl dipeptide derivatives containing a quinonyl moiety via aminoacyl intermediates.通过氨酰基中间体合成含有醌基部分的免疫活性胞壁酰二肽衍生物。
Chem Pharm Bull (Tokyo). 1981 Aug;29(8):2215-21. doi: 10.1248/cpb.29.2215.
5
Synthesis and immunoadjuvant activities of muramoyl-L-alanyl-D-isoglutamine and some carbohydrate analogs.胞壁酰-L-丙氨酰-D-异谷氨酰胺及一些碳水化合物类似物的合成与免疫佐剂活性
Carbohydr Res. 1980 Feb;79(1):C17-9. doi: 10.1016/s0008-6215(00)85145-9.
6
Synthesis of N-acetyl-6-amino- and -6-(acylamino)-6-deoxymuramoyl dipeptides, and their immunoadjuvant activities.N-乙酰-6-氨基-和-6-（酰基氨基）-6-脱氧Muramoyl二肽的合成及其免疫佐剂活性。
Carbohydr Res. 1980 Feb;79(1):C20-3. doi: 10.1016/s0008-6215(00)85146-0.
7
Synthesis, mass spectral characterization and immunoadjuvant activity of some novel lipophilic derivatives of muramyl dipeptides.一些新型亲脂性胞壁酰二肽衍生物的合成、质谱表征及免疫佐剂活性
Chem Phys Lipids. 1986 Oct-Nov;41(3-4):237-64. doi: 10.1016/0009-3084(86)90025-3.
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[Synthesis and protective activity of beta-glycosides of N-acetylmuramyl-L-alanyl-D-isoglutamine with alkylalicyclic and arylaliphatic aglycons].[具有脂环族和芳脂族苷元的 N-乙酰胞壁酰-L-丙氨酰-D-异谷氨酰胺β-糖苷的合成及保护活性]
Bioorg Khim. 2005 Nov-Dec;31(6):637-44.
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[Chemical synthesis and immunologic activities of the active unit of BCG-CWS].
Nihon Rinsho. 1981 Apr;39(4):1861-7.
10
Synthesis and immunoadjuvant activity of N-[2-O-(2-acetamido- 1,2,3,5-tetradeoxy-1,5-imino-D-glucitol-3-yl)-D-lactoyl]- L-alanyl-D-isoglutamine.N-[2-O-(2-乙酰氨基-1,2,3,5-四脱氧-1,5-亚氨基-D-葡糖醇-3-基)-D-乳酰基]-L-丙氨酰-D-异谷氨酰胺的合成及其免疫佐剂活性
Carbohydr Res. 1990 Dec 15;208:267-72. doi: 10.1016/0008-6215(90)80109-g.

引用本文的文献

1
Structure-activity relationship in NOD2 agonistic muramyl dipeptides.NOD2 激动型 muramyl dipeptides 的结构-活性关系。
Eur J Med Chem. 2024 May 5;271:116439. doi: 10.1016/j.ejmech.2024.116439. Epub 2024 Apr 20.
2
Structural Fine-Tuning of Desmuramylpeptide NOD2 Agonists Defines Their Adjuvant Activity.结构精细调整脱酰基肽 NOD2 激动剂定义了它们的佐剂活性。
J Med Chem. 2021 Jun 10;64(11):7809-7838. doi: 10.1021/acs.jmedchem.1c00644. Epub 2021 May 27.
3
Sleep-promoting effects of muramyl peptides.胞壁酰肽的促睡眠作用。
Proc Natl Acad Sci U S A. 1982 Oct;79(19):6102-6. doi: 10.1073/pnas.79.19.6102.
4
Regulation by muramyl dipeptide (MDP) of the lymphoproliferative responses and polyclonal activation of human peripheral blood mononuclear cells.胞壁酰二肽（MDP）对人外周血单个核细胞增殖反应及多克隆激活的调节作用
Clin Exp Immunol. 1984 Jul;57(1):178-86.
5
Enhancement by murabutide of the immune response to natural and synthetic hepatitis B surface antigens.莫拉司亭对天然和合成乙肝表面抗原免疫反应的增强作用。
Infect Immun. 1984 Jul;45(1):261-6. doi: 10.1128/iai.45.1.261-266.1984.
6
Comparison of immunomodulatory activities in mice and guinea pigs of a synthetic desmuramyl peptidolipid triglymyc.合成去 muramyl 肽脂 Triglymyc 在小鼠和豚鼠体内免疫调节活性的比较。
Infect Immun. 1984 Mar;43(3):870-5. doi: 10.1128/iai.43.3.870-875.1984.
7
Muramyl peptides. Variation of somnogenic activity with structure.胞壁酰肽。催眠活性随结构的变化。
J Exp Med. 1984 Jan 1;159(1):68-76. doi: 10.1084/jem.159.1.68.
8
Two adjuvant-active muramyl dipeptide analogs induce differential production of lymphocyte-activating factor and a factor causing distress in guinea pigs.两种具有佐剂活性的胞壁酰二肽类似物可诱导豚鼠产生不同水平的淋巴细胞激活因子和一种引起不适的因子。
Infect Immun. 1984 May;44(2):344-50. doi: 10.1128/iai.44.2.344-350.1984.
9
Modulation of myelopoiesis in vivo by synthetic adjuvant-active muramyl peptides: induction of colony-stimulating activity and stimulation of stem cell proliferation.合成佐剂活性胞壁酰肽对体内骨髓生成的调节：集落刺激活性的诱导及干细胞增殖的刺激
Infect Immun. 1983 Dec;42(3):1081-5. doi: 10.1128/iai.42.3.1081-1085.1983.
10
Immunotherapy of Lewis lung carcinoma with hydrosoluble peptidoglycan monomer (PGM).水溶性肽聚糖单体（PGM）对Lewis肺癌的免疫治疗
Cancer Immunol Immunother. 1983;15(2):84-6. doi: 10.1007/BF00199695.