Shinogi M, Nakazawa M, Fukuda K, Mori I
Radioisotopes. 1982 Feb;31(2):78-81. doi: 10.3769/radioisotopes.31.2_78.
Six elements, Cd, Co, Cu, Mn, Se and Zn, in the metallothionein fractions from liver of rat injected various metals (Cd, Co, Cu, Hg, Se and Zn) were analyzed by neutron activation analysis and were investigated metal binding of it. The concentrations of Cd and Zn were increased by administration of Cd and those of Co and Se were also increased by administration of the each element. On the contrary, the concentration of Cd and Cu were decreased by administration of Se. It may be considered that Co and Se are attached to metallothionein, if its protein is present and the presence of Se influence the binding of Cu and Cd to metallothionein, further it also influence Cd-thionein production.
通过中子活化分析对注射了各种金属（镉、钴、铜、汞、硒和锌）的大鼠肝脏金属硫蛋白组分中的六种元素镉、钴、铜、锰、硒和锌进行了分析，并研究了其金属结合情况。给予镉后镉和锌的浓度升高，给予每种元素后钴和硒的浓度也升高。相反，给予硒后镉和铜的浓度降低。可以认为，如果存在金属硫蛋白，钴和硒会与之结合，并且硒的存在会影响铜和镉与金属硫蛋白的结合，进而也会影响镉硫蛋白的产生。
