Vaernes R, Bennett P B, Hammerborg D, Ellertsen B, Peterson R E, Tøonjum S
Undersea Biomed Res. 1982 Mar;9(1):1-14.
Two groups of divers were compressed to 300 msw (984 fsw) with heliox (n = 3) and trimix (n = 3). Neuropsychological/neurological testing was performed repeatedly during the compression and on reaching 250 (820 fsw) and 300 msw. On the second day the trimix group was tested before and after a gas change to heliox. For the heliox group there was a marked increase in tremor and EEG slow waves, and reduction of alpha band and in hand-grip strength. For the trimix group visuomotor coordination was impaired. In the cognitive performance tests the heliox group was most impaired at 250 msw, whereas the trimix group was most impaired at 300 msw. Before the gas change to heliox the trimix group showed impaired performance in some tests. After the gas change, performance returned to predive levels, except for perceptual speed. There was an increase in tremor immediately after the gas change.
There was a marked HPNS effect during compression on heliox. This effect was not observed in the trimix group, but this group was mildly intoxicated on reaching saturation depth. The tests indicated slight narcotic effects also after 26 h, but this disappeared after the change in heliox.
两组潜水员分别使用氦氧混合气（n = 3）和 Trimix（n = 3）被压缩至300米海水深度（984英尺海水深度）。在压缩过程中以及到达250米（820英尺海水深度）和300米海水深度时反复进行神经心理学/神经学测试。第二天，Trimix组在更换为氦氧混合气前后进行了测试。对于氦氧混合气组，震颤和脑电图慢波明显增加，α波段和握力降低。对于Trimix组，视运动协调受损。在认知性能测试中，氦氧混合气组在250米海水深度时受损最严重，而Trimix组在300米海水深度时受损最严重。在更换为氦氧混合气之前，Trimix组在一些测试中表现受损。更换气体后，除感知速度外，性能恢复到潜水前水平。更换气体后立即出现震颤增加。
在使用氦氧混合气压缩过程中存在明显的高压神经综合征效应。在Trimix组未观察到这种效应，但该组在达到饱和深度时出现轻度中毒。测试表明，26小时后也有轻微的麻醉作用，但更换为氦氧混合气后这种作用消失。
