Seifert B, Hassler M P, Herter U
Zentralbl Gynakol. 1982;104(1):45-51.
Minprostin-F2 alpha was injected intravenously to 20 women, and 15(S)-15-methyl-PG F2 alpha was intramuscularly injected to 19 women to induce abortion. All patients were in early pregnancy, none of them beyond the seventh week. The steroid hormones 17 beta-oestradiol and progesterone were reduced to 75 per cent of their initial concentrations in all cases of successful induction. HCG levels in plasma dropped with some delay.--The results are likely to suggest that the above decline of steroid hormones in response to abortion induced in early pregnancy was attributable to secondary regression of corpus luteum.
向20名女性静脉注射地诺前列素F2α，并向19名女性肌肉注射15（S）-15-甲基前列腺素F2α以诱导流产。所有患者均处于早孕阶段，无一超过孕7周。在所有成功引产的病例中，甾体激素17β-雌二醇和孕酮降至其初始浓度的75%。血浆中的人绒毛膜促性腺激素（HCG）水平有所延迟下降。——结果可能表明，早孕流产引起的上述甾体激素下降归因于黄体的继发性退化。
