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早期妊娠中激素浓度对前列腺素诱导流产的反应(作者译)

[Concentration of hormones in early pregnancy in response to prostaglandin-induced abortion (author's transl)].

作者信息

Seifert B, Hassler M P, Herter U

出版信息

Zentralbl Gynakol. 1982;104(1):45-51.

PMID:7090630
Abstract

Minprostin-F2 alpha was injected intravenously to 20 women, and 15(S)-15-methyl-PG F2 alpha was intramuscularly injected to 19 women to induce abortion. All patients were in early pregnancy, none of them beyond the seventh week. The steroid hormones 17 beta-oestradiol and progesterone were reduced to 75 per cent of their initial concentrations in all cases of successful induction. HCG levels in plasma dropped with some delay.--The results are likely to suggest that the above decline of steroid hormones in response to abortion induced in early pregnancy was attributable to secondary regression of corpus luteum.

摘要

向20名女性静脉注射地诺前列素F2α,并向19名女性肌肉注射15(S)-15-甲基前列腺素F2α以诱导流产。所有患者均处于早孕阶段,无一超过孕7周。在所有成功引产的病例中,甾体激素17β-雌二醇和孕酮降至其初始浓度的75%。血浆中的人绒毛膜促性腺激素(HCG)水平有所延迟下降。——结果可能表明,早孕流产引起的上述甾体激素下降归因于黄体的继发性退化。

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