Marshall J B, Gerhardt D C
Am J Gastroenterol. 1982 Jun;77(6):351-4.
We report two patients with reflux esophagitis who had decreased lower esophageal sphincter pressures and marked decreased frequency of peristaltic response to swallowing and peristaltic amplitude on pretreatment esophageal motility tracings. Both patients responded to medical therapy of reflux esophagitis with symptomatic clinical improvement, increased lower esophageal sphincter pressures, and increased frequency of peristaltic propagation and amplitude of peristalsis. Measures to treat reflux esophagitis may be effective in some cases, in part, because they permit healing of esophageal inflammation to improve esophageal motor activity, the latter which results in improvement of esophageal acid clearing.
我们报告了两名反流性食管炎患者，他们在治疗前的食管动力描记图上显示食管下括约肌压力降低，对吞咽的蠕动反应频率显著降低，蠕动幅度减小。两名患者接受反流性食管炎药物治疗后，临床症状均有改善，食管下括约肌压力增加，蠕动传播频率和蠕动幅度也增加。治疗反流性食管炎的措施在某些情况下可能有效，部分原因是它们能使食管炎症愈合，从而改善食管运动功能，进而提高食管酸清除能力。
