Hayashi K, Yabuki T, Tabuchi K, Fujii T
Arch Orthop Trauma Surg (1978). 1982;99(4):265-9. doi: 10.1007/BF00381405.
Collagen solution extracted from the adult steer hide was mixed with the synthesized hydroxyapatite and after cross linking lyophilized. Small blocks of this sample were filled in bone defects of rabbit fibula. Two control groups were made, of which one was filled with the collagen block contained no apatite and the other group left as a sham operation. The experimental group showed more active bone formation than control groups.
从成年公牛皮中提取的胶原蛋白溶液与合成的羟基磷灰石混合，交联后冻干。将该样品的小块填充到兔腓骨的骨缺损处。设立两个对照组，其中一个填充不含磷灰石的胶原蛋白块，另一个作为假手术组。实验组显示出比对照组更活跃的骨形成。
