Thomas J M, Fitzharris B M, Redding W H, Williams J E, Trott P A, Powles T J, Ford H T, Gazet J C
Br Med J. 1978 Oct 21;2(6145):1139-41. doi: 10.1136/bmj.2.6145.1139.
The diagnostic accuracy of clinical examination, xeromammography, and fine-needle aspiration cytology was compared with definitive histological findings in 255 breast lumps excised during one year. When suitable aspirates were obtained for cytological examination the diagnostic accuracy of aspiration cytology was higher than clinical examination or xeromammography. A diagnostic accuracy of 99% was achieved when all three screening tests were in agreement. As well as confirming a clinical diagnosis of malignancy, cytology is useful in identifying malignancy when clinical findings suggest that the tumour is benign. The availability of accurate cytology has affected patient management in many ways. Xeromammography did not enhance the diagnostic accuracy of clinical examination and aspiration cytology in patients presenting with a breast lump and, as a procedure with potential hazard, the benefit of routine xeromammography is questionable when an efficient cytological service is available.
对一年内切除的255个乳腺肿块的临床检查、干板乳房X线照相术和细针穿刺细胞学检查的诊断准确性与最终组织学结果进行了比较。当获得合适的吸出物用于细胞学检查时,穿刺细胞学检查的诊断准确性高于临床检查或干板乳房X线照相术。当所有三项筛查试验结果一致时,诊断准确性可达99%。细胞学检查不仅可以证实恶性肿瘤的临床诊断,在临床检查提示肿瘤为良性时,也有助于识别恶性肿瘤。准确的细胞学检查在很多方面影响了患者的治疗。对于有乳腺肿块的患者,干板乳房X线照相术并未提高临床检查和穿刺细胞学检查的诊断准确性,而且作为一种有潜在风险的检查方法,在有高效细胞学检查服务的情况下,常规干板乳房X线照相术的益处值得怀疑。