Abinader E G, Shahar J
Br Heart J. 1982 Aug;48(2):130-3. doi: 10.1136/hrt.48.2.130.
Exercise electrocardiograms must be interpreted with the understanding that not every positive test is indicative of coronary artery disease. Mitral valve prolapse mimics coronary heart disease clinically and often in the electrocardiographic response to exercise. Twelve patients with mitral valve prolapse in whom exercise testing was positive underwent a repeat study after beta blockade. All tracings returned to normal after adequate blockade, evidenced by 17 to 22% reduction of resting and exercise heart rates. To the best of our knowledge, this is the first such report in the English literature. The results of this study suggest that an exercise test after beta blockade should become part of the routine procedure in such patients. The elimination of false positive electrocardiographic responses by beta blockade should help improve the specificity of the exercise test. Moreover, similar responses should lead to the suspicion of mitral valve prolapse.
运动心电图的解读必须明白，并非每次阳性检查结果都提示冠状动脉疾病。二尖瓣脱垂在临床及运动心电图反应方面常酷似冠心病。12例运动试验阳性的二尖瓣脱垂患者在接受β受体阻滞剂治疗后进行了重复检查。在充分阻滞（静息心率和运动心率降低17%至22%）后，所有心电图记录均恢复正常。据我们所知，这是英文文献中首次出现此类报告。本研究结果提示，β受体阻滞剂治疗后的运动试验应成为此类患者常规检查的一部分。β受体阻滞剂消除心电图假阳性反应应有助于提高运动试验的特异性。此外，类似反应应引起对二尖瓣脱垂的怀疑。
