Arnold A G, Lane D J, Zapata E
Br J Dis Chest. 1982 Apr;76(2):157-63.
The speed of onset of attacks of acute severe asthma was prospectively studied in a total of 261 consecutive episodes. 82% of these episodes involved patients with 'extrinsic' asthma and 28% involved children. The speed of onset of an attack was rapid (defined as less than 24 hours) in 46% of episodes and was less than one hour in 13%. Rapid-onset attacks occurred more frequently in younger patients and were no more or less severe than attacks of slower evolution. Comparison of different measures of severity in our patients showed statistically significant but low correlations. Objective measures seemed no better than simple clinical assessment with the Jones index. We discuss the significance of these correlations and the place of emergency admission services for attacks of acute severe asthma of rapid speed of onset.
对261例连续性急性重症哮喘发作的起病速度进行了前瞻性研究。其中82%的发作涉及“外源性”哮喘患者，28%涉及儿童。46%的发作起病迅速（定义为少于24小时），13%的发作起病少于1小时。起病迅速的发作在年轻患者中更常见，其严重程度与起病较慢的发作并无差异。对我们患者不同严重程度测量指标的比较显示，相关性具有统计学意义但较低。客观指标似乎并不比用琼斯指数进行的简单临床评估更好。我们讨论了这些相关性的意义以及针对起病迅速的急性重症哮喘发作的急诊入院服务的作用。
