Shaĭtan K V, Rubin A B
Biofizika. 1982 May-Jun;27(3):386-90.
A mathematical model is developed for conformational motions of proteins. The mechanism is shown to be by local jump diffusion via conformational substrates. The model is analysed in terms of experimental data obtained by Mössbauer spectroscopy and X-ray scattering. From comparative analysis the validity of a continual model is deduced. The correlation between electron transport activity and protein conformation motions is discussed within the local jump mechanism. An equation is established to describe the relationship between electron tunneling rate and correlation time of conformational movement.
建立了一个蛋白质构象运动的数学模型。结果表明,其机制是通过构象底物进行局部跳跃扩散。根据通过穆斯堡尔光谱和X射线散射获得的实验数据分析该模型。通过比较分析推导出连续模型的有效性。在局部跳跃机制内讨论了电子传输活性与蛋白质构象运动之间的相关性。建立了一个方程来描述电子隧穿速率与构象运动相关时间之间的关系。