牛宫颈黏液的流动渗透分析
Flow permeation analysis of bovine cervical mucus.
作者信息
Katz D F, Tam P Y, Berger S A, Sensabaugh G F
出版信息
Biophys J. 1982 May;38(2):153-9. doi: 10.1016/S0006-3495(82)84542-6.
Geometrical properties of the microstructure of whole bovine cervical mucus were studied. An experimental technique was developed for measuring the flow of fluid through the mucus microstructure in response to application or a prescribed external pressure gradient. The data obtained were analyzed in conjunction with a mathematical model of the hydrodynamics of the flow-permeation process. The sizes of typical interstices within the microstructure were calculated to be of the order of 1 micrometer, with typical macromolecular filament diameters being of the order of 100 A. These dimensions were interpreted as representative of an equivalent network giving rise to measured flow permeability. The values of filament size showed a strong experimental correlation with the solids content of the mucus.
研究了整个牛宫颈黏液微观结构的几何特性。开发了一种实验技术，用于测量在施加规定的外部压力梯度时流体通过黏液微观结构的流动情况。将获得的数据与流动渗透过程流体动力学的数学模型相结合进行分析。计算得出微观结构内典型孔隙的尺寸约为1微米，典型大分子细丝直径约为100埃。这些尺寸被解释为产生测得的流动渗透率的等效网络的代表。细丝尺寸的值与黏液的固体含量显示出很强的实验相关性。
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