Bragin E O, Vasilenko G F, Durinian R A
Biull Eksp Biol Med. 1982 May;93(5):22-4.
Electrolytic lesions of central gray matter (CGM) were induced in rats. The analgesia produced by stress (foot shock) tested by the hot-plate and tail-flick method was significantly and substantially reduced in the lesioned rats. The baseline pain threshold measured by the hot-plate method was significantly longer in CGM-lesioned rats. The baseline tail-flick latency was unaffected by the lesions. The role of CGM in the regulation of pain sensitivity in rats is discussed.
在大鼠中诱导了中央灰质（CGM）的电解损伤。通过热板法和甩尾法测试，损伤大鼠中由应激（足部电击）产生的镇痛作用显著且大幅降低。通过热板法测量的基线疼痛阈值在CGM损伤大鼠中显著延长。基线甩尾潜伏期不受损伤影响。本文讨论了CGM在调节大鼠疼痛敏感性中的作用。
