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仓鼠视神经突触体膜中[3H]岩藻糖基糖肽的产后变化

Postnatal changes in [3H]fucosyl glycopeptides of hamster optic nerve synaptosomal membrane.

作者信息

Specht S C

出版信息

Brain Res. 1982 May;256(1):109-14. doi: 10.1016/0165-3806(82)90102-x.

DOI:10.1016/0165-3806(82)90102-x
PMID:7093723
Abstract

Axonally transported glycopeptides of the optic nerve synaptosomal membrane were labeled in neonatal and adult hamsters by intraocular injection of [3H]fucose. A prominent polypeptide in the 50,000 molecular weight region was heavily labeled after eye-opening in 16-day-old and adult hamsters, but not in 5- or 12-day-olds. The data suggest that either synthesis or fucosylation of a major synaptosomal membrane glycopeptide is under developmental control and expressed primarily after the eye-lids open.

摘要

通过眼内注射[3H]岩藻糖,在新生和成年仓鼠中标记视神经突触体膜的轴突运输糖肽。在16日龄和成年仓鼠睁眼后,50,000分子量区域的一种突出多肽被大量标记,但在5日龄或12日龄仓鼠中未被标记。数据表明,主要突触体膜糖肽的合成或岩藻糖基化受发育控制,且主要在眼睑张开后表达。

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1
Postnatal changes in [3H]fucosyl glycopeptides of hamster optic nerve synaptosomal membrane.仓鼠视神经突触体膜中[3H]岩藻糖基糖肽的产后变化
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2
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引用本文的文献

1
Postnatal changes in [3H]fucosyl glycoconjugates axonally transported into hamster optic nerve endings.轴突运输至仓鼠视神经末梢的[3H]岩藻糖基糖缀合物的出生后变化。
Neurochem Res. 1984 Jan;9(1):59-71. doi: 10.1007/BF00967659.
2
Effects of neonatal intraocular colchicine on synaptogenesis and on the retention of the ipsilateral retinofugal projection within the superior colliculus.新生期眼内注射秋水仙碱对突触形成及上丘同侧视网膜神经纤维投射保留的影响。
Exp Brain Res. 1985;60(3):465-82. doi: 10.1007/BF00236932.